Monoclonal anti-Human, MAPK1 antibody (AT1A4)

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Product name Monoclonal anti-Human, MAPK1 antibody (AT1A4)
Catalog no 4ab060160
Size 50ul
Background Mitogen-activated protein kinases (MAPKs) are reported to be critical regulatory factors for the growth andmigration of various cell types including vascular smooth muscle cells (VSMCs). It has also been reported that the activation of the MAP kinase family, extracellular signal regulated kinases 1/2 (ERK1/2), and c-Jun N-terminal kinase (JNK) via Src activation is important for AII-induced migration of VSMCs. MAPKs are intracellular signal-transduction pathways that have been shown to play a central role in the development of injury following ischemia in the brain and heart. MAPKs regulate gene expression, which is important in cell injury/repair and proliferation/differentiation.
Storage Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
Predict MW
Synonyms Mitogen-activated protein kinase 1, ERK, ERK2, ERT1, MAPK2, p38, p40, p41, p41mapk, P42MAPK, PRKM1, PRKM2, Mitogen-activated protein kinase 1 MAP kinase 2, MAPK 2, ERK 2, Extracellular Signal Regulated Kinase 2, MAPK 1.


Conjugate Unconjugated
Tested application ELISA, WB, Immunofluorescence
Clonality Monoclonal
Isotype IgG2b, k
Host mouse
Immunogen Recombinant human MAPK1 (1-360) purified from E.coli
Reactivity Human

image of Monoclonal anti-Human, MAPK1 antibody (AT1A4)

应用 Ab评论 说明
IHC-Fr 1/200.
CHIPseq Use at an assay dependent concentration.
Dot blot 1/10000.
IHC-P 1/100 - 1/400. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
Electron 1/50. Customer feedback
ChIP Use 2µg for 106 cells
IP Use a concentration of 5 µg/ml.
WB 1/1000 - 1/5000. Detects a band of approximately 17 kDa (predicted molecular weight: 15 kDa).
ChIP/Chip Use at an assay dependent concentration.
IHC - Use at an assay dependent concentration. PubMed: 22219645
ICC 1/100 - 1/500.

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